Review



htnfr2  (R&D Systems)


Bioz Verified Symbol R&D Systems is a verified supplier
Bioz Manufacturer Symbol R&D Systems manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 94
      Buy from Supplier

    Structured Review

    R&D Systems htnfr2
    Fig. 2. Characterization of anti-mTNFR2 mAbs targeting CRDs 1–4. (A) Schematic representation of the 6 mouse-human TNF2 chimeras CRD1-CRD4 (Cystein Rich Domain). (B) The targeting CRD of each mAb were determined by cell ELISA with mouse-human TNFR2 domain swap mutants. Data represented as a three-parameter OD450–620 detection based on mean and SD of three independent experiments. (C) The domain epitopes of the 13 mAbs are indicated on a <t>hTNFR2-hTNFα</t> trimer structure (PDB: 3ALQ), 74% similar to mouse TNFR2. The CRDs for one TNFR2 receptor are shown in indicated colors.
    Htnfr2, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 13 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/htnfr2/pm34699840-53-20-21?v=R%26D+Systems
    Average 94 stars, based on 13 article reviews
    htnfr2 - by Bioz Stars, 2026-08
    94/100 stars

    Images

    1) Product Images from "Generation and characterization of novel co-stimulatory anti-mouse TNFR2 antibodies."

    Article Title: Generation and characterization of novel co-stimulatory anti-mouse TNFR2 antibodies.

    Journal: Journal of immunological methods

    doi: 10.1016/j.jim.2021.113173

    Fig. 2. Characterization of anti-mTNFR2 mAbs targeting CRDs 1–4. (A) Schematic representation of the 6 mouse-human TNF2 chimeras CRD1-CRD4 (Cystein Rich Domain). (B) The targeting CRD of each mAb were determined by cell ELISA with mouse-human TNFR2 domain swap mutants. Data represented as a three-parameter OD450–620 detection based on mean and SD of three independent experiments. (C) The domain epitopes of the 13 mAbs are indicated on a hTNFR2-hTNFα trimer structure (PDB: 3ALQ), 74% similar to mouse TNFR2. The CRDs for one TNFR2 receptor are shown in indicated colors.
    Figure Legend Snippet: Fig. 2. Characterization of anti-mTNFR2 mAbs targeting CRDs 1–4. (A) Schematic representation of the 6 mouse-human TNF2 chimeras CRD1-CRD4 (Cystein Rich Domain). (B) The targeting CRD of each mAb were determined by cell ELISA with mouse-human TNFR2 domain swap mutants. Data represented as a three-parameter OD450–620 detection based on mean and SD of three independent experiments. (C) The domain epitopes of the 13 mAbs are indicated on a hTNFR2-hTNFα trimer structure (PDB: 3ALQ), 74% similar to mouse TNFR2. The CRDs for one TNFR2 receptor are shown in indicated colors.

    Techniques Used: Enzyme-linked Immunosorbent Assay



    Similar Products

    htnfr2  (PeproTech)
    90
    PeproTech htnfr2
    Htnfr2, supplied by PeproTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/htnfr2/bio_rxiv__2024__12__09__627526-201-23-25?v=PeproTech
    Average 90 stars, based on 1 article reviews
    htnfr2 - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier
    ct26-htnfr2 ki cell line  (GemPharmatech Co Ltd)
    90
    GemPharmatech Co Ltd ct26-htnfr2 ki cell line
    Ct26 Htnfr2 Ki Cell Line, supplied by GemPharmatech Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/htnfr2/pm39033663-59-1-8?v=GemPharmatech+Co+Ltd
    Average 90 stars, based on 1 article reviews
    ct26-htnfr2 ki cell line - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier
    balb/c-htnfr2 ki mice  (GemPharmatech Co Ltd)
    90
    GemPharmatech Co Ltd balb/c-htnfr2 ki mice
    Balb/C Htnfr2 Ki Mice, supplied by GemPharmatech Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/htnfr2/pm39033663-60-13-18?v=GemPharmatech+Co+Ltd
    Average 90 stars, based on 1 article reviews
    balb/c-htnfr2 ki mice - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier
    anti-htnfr2 higg1  (Apexigen Inc)
    90
    Apexigen Inc anti-htnfr2 higg1
    Anti Htnfr2 Higg1, supplied by Apexigen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/htnfr2/pmc10758050__thnov14p0496s1-53-44-71?v=Apexigen+Inc
    Average 90 stars, based on 1 article reviews
    anti-htnfr2 higg1 - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier
    htnfr2  (ImmunoGen Inc)
    90
    ImmunoGen Inc htnfr2
    Htnfr2, supplied by ImmunoGen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/htnfr2/pmc09958373-66-9-22?v=ImmunoGen+Inc
    Average 90 stars, based on 1 article reviews
    htnfr2 - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier
    htnfr2  (R&D Systems)
    94
    R&D Systems htnfr2
    Fig. 2. Characterization of anti-mTNFR2 mAbs targeting CRDs 1–4. (A) Schematic representation of the 6 mouse-human TNF2 chimeras CRD1-CRD4 (Cystein Rich Domain). (B) The targeting CRD of each mAb were determined by cell ELISA with mouse-human TNFR2 domain swap mutants. Data represented as a three-parameter OD450–620 detection based on mean and SD of three independent experiments. (C) The domain epitopes of the 13 mAbs are indicated on a <t>hTNFR2-hTNFα</t> trimer structure (PDB: 3ALQ), 74% similar to mouse TNFR2. The CRDs for one TNFR2 receptor are shown in indicated colors.
    Htnfr2, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/htnfr2/pm34699840-53-20-21?v=R%26D+Systems
    Average 94 stars, based on 1 article reviews
    htnfr2 - by Bioz Stars, 2026-08
    94/100 stars
    		  Buy from Supplier
    polyclonal goat-anti-htnfr2  (R&D Systems)
    90
    R&D Systems polyclonal goat-anti-htnfr2
    Fig. 2. Characterization of anti-mTNFR2 mAbs targeting CRDs 1–4. (A) Schematic representation of the 6 mouse-human TNF2 chimeras CRD1-CRD4 (Cystein Rich Domain). (B) The targeting CRD of each mAb were determined by cell ELISA with mouse-human TNFR2 domain swap mutants. Data represented as a three-parameter OD450–620 detection based on mean and SD of three independent experiments. (C) The domain epitopes of the 13 mAbs are indicated on a <t>hTNFR2-hTNFα</t> trimer structure (PDB: 3ALQ), 74% similar to mouse TNFR2. The CRDs for one TNFR2 receptor are shown in indicated colors.
    Polyclonal Goat Anti Htnfr2, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/htnfr2/us10775385-1227-15-17?v=R%26D+Systems
    Average 90 stars, based on 1 article reviews
    polyclonal goat-anti-htnfr2 - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier
    htnfr2-fc  (Millipore)
    90
    Millipore htnfr2-fc
    TABLE 3
    Htnfr2 Fc, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/htnfr2/pmc04481203-191-22-29?v=Millipore
    Average 90 stars, based on 1 article reviews
    htnfr2-fc - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Fig. 2. Characterization of anti-mTNFR2 mAbs targeting CRDs 1–4. (A) Schematic representation of the 6 mouse-human TNF2 chimeras CRD1-CRD4 (Cystein Rich Domain). (B) The targeting CRD of each mAb were determined by cell ELISA with mouse-human TNFR2 domain swap mutants. Data represented as a three-parameter OD450–620 detection based on mean and SD of three independent experiments. (C) The domain epitopes of the 13 mAbs are indicated on a hTNFR2-hTNFα trimer structure (PDB: 3ALQ), 74% similar to mouse TNFR2. The CRDs for one TNFR2 receptor are shown in indicated colors.

    Journal: Journal of immunological methods

    Article Title: Generation and characterization of novel co-stimulatory anti-mouse TNFR2 antibodies.

    doi: 10.1016/j.jim.2021.113173

    Figure Lengend Snippet: Fig. 2. Characterization of anti-mTNFR2 mAbs targeting CRDs 1–4. (A) Schematic representation of the 6 mouse-human TNF2 chimeras CRD1-CRD4 (Cystein Rich Domain). (B) The targeting CRD of each mAb were determined by cell ELISA with mouse-human TNFR2 domain swap mutants. Data represented as a three-parameter OD450–620 detection based on mean and SD of three independent experiments. (C) The domain epitopes of the 13 mAbs are indicated on a hTNFR2-hTNFα trimer structure (PDB: 3ALQ), 74% similar to mouse TNFR2. The CRDs for one TNFR2 receptor are shown in indicated colors.

    Article Snippet: Immunoreactivity to mouse TNFR2 and cross-reactivity to human TNFR2 was assessed by ELISA using recombinant mTNFR2/Fc-protein (R&D Systems, 9707-R2) and hTNFR2 (R&D Systems, 726-R2) as well as CHO-K1.mTNFR2 and CHO-K1.hTNFR2.

    Techniques: Enzyme-linked Immunosorbent Assay

    TABLE 3

    Journal: The Journal of Biological Chemistry

    Article Title: Comparative Biochemical and Functional Analysis of Viral and Human Secreted Tumor Necrosis Factor (TNF) Decoy Receptors *

    doi: 10.1074/jbc.M115.650119

    Figure Lengend Snippet: TABLE 3

    Article Snippet: Recombinant His-tagged proteins were purified from supernatants of Hi5 cells infected at high multiplicity using nickel-nitrilotriacetic acid columns (Qiagen) ( 22 ). hTNFR2-Fc was purified using protein A-coupled Sepharose (Sigma) followed by size exclusion chromatography.

    Techniques: Derivative Assay, Binding Assay